Batman/Powerpuff Girls

Heroes and Villains
Dr. Pamela Lillian Isley/Poison Ivy as Blossom (Both have orange hair)

Selina Kyle/Catwoman as Bubbles

Dr. Harleen Quinzel/Harley Quinn as Buttercup

The Joker as Mojo Jojo

Dr. Johnathan Crane/the Scarecrow as Brick

Bruce Wayne/Batman as Boomer

Dick Grayson/Robin as Butch

Mary Dahl/Baby Doll as Princess Morbucks

Jervis Tech/the Mad Hatter as Snake

Alfred Pennyworth as Professor Utonium

Summer Gleeson as Ace

Commisioner James Gordon as The Mayor